Using Wellbutrin for Anxiety: Does It Help or Hurt?
- Jason Galdo
- Apr 8
- 2 min read

Using Wellbutrin for Anxiety: Does It Help or Hurt?
Anxiety is a beast. It can steal your peace, sabotage your sleep, and make everyday situations feel like insurmountable challenges. Naturally, people search for relief wherever they can find it. One medication that’s become part of the conversation is
Wellbutrin (bupropion), an antidepressant originally designed to treat depression and help people quit smoking. But can it really help with anxiety? Or is it just adding fuel to the fire?
What is Wellbutrin?
Wellbutrin is a norepinephrine-dopamine reuptake inhibitor (NDRI). That’s a fancy way of saying it works differently than most antidepressants, which typically target serotonin. Instead, Wellbutrin boosts the brain chemicals dopamine and norepinephrine, which are linked to mood, energy, and motivation.
Doctors often prescribe it for depression and sometimes for attention-deficit disorders or smoking cessation. But when it comes to anxiety, Wellbutrin is a bit of a wildcard.
The Case For Wellbutrin Helping Anxiety
Some people swear by it. They say Wellbutrin lifts the fog of depression and helps with the fatigue that often comes with anxious feelings. It can give you that extra push to get out of bed, tackle your day, and face your worries head-on.
In cases where anxiety is tied to depression, Wellbutrin may help by improving overall mood and energy levels. If your anxiety stems from feeling stuck, tired, or emotionally drained, Wellbutrin could be a step in the right direction.
The Case Against Wellbutrin Helping Anxiety
But here’s the catch: Wellbutrin can also increase anxiety in some people. Because it stimulates the brain, it may lead to restlessness, irritability, racing thoughts, and even panic attacks—especially in those prone to high anxiety or sensitivity to medication.
That’s why doctors usually don’t prescribe Wellbutrin as a first-line treatment for generalized anxiety disorder (GAD) or panic disorders. It’s not typically the go-to for calming an anxious mind.
So, Should You Try It?
It really depends on the person. If your anxiety is part of a bigger picture that includes depression or ADHD, Wellbutrin might offer a unique benefit. If your anxiety is standalone and already intense, it may make things worse.
This is where sobriety and mental clarity come into the conversation. Many people turn to prescription meds, alcohol, or other substances to cope with their anxiety. But the truth is, these can create more problems than they solve.
Life Is Short. Sobriety Is Best.
Whether it’s alcohol, pills, or any other crutch, leaning too heavily on something outside of yourself can keep you from finding true peace. Sobriety isn’t about perfection—it’s about clarity, freedom, and feeling like yourself again. You don’t have to be stuck in cycles of dependence, stress, or masking symptoms.
If you're considering Wellbutrin, have an honest conversation with your doctor. Weigh the pros and cons. And more importantly, take a moment to ask what you're really looking for: relief or escape? Healing or hiding?
Mental health is complex, and there’s no one-size-fits-all answer. But living clearly, choosing sobriety, and finding tools that truly support your journey can make a world of difference.
Because life’s too short to feel like you’re just surviving.
Choose to thrive.
If you or a loved one are struggling with mental health issues, please give us a call today at 833-479-0797.
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